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Study for anlotinib in the treatment of brain metastasis of non-small cell lung cancer

Study for anlotinib in the treatment of brain metastasis of non-small cell lung cancer

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023190
Enrollment
Unknown
Registered
2019-05-16
Start date
2019-06-01
Completion date
Unknown
Last updated
2019-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

none small cell lung cancer

Interventions

Sponsors

Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-75 years old; 2. pathological diagnosis of patients with advanced (IIIB/IV) NSCLC; 3. has at least one measurable lesion; 4. KPS score =40; 5. Obtain informed consent signed by the patient or his legal representative 6. Preliminary patients with brain metastasis

Exclusion criteria

Exclusion criteria: 1. Before the study, the routine blood function of the liver function and abnormal electrocardiogram examination; 2. patients with any signs or history of bleeding physique; 3. symptomatic brain metastasis; 4. small cell lung cancer, including small cell carcinoma and non-small cell carcinoma mixed lung cancer; 5. patients with tumours that have invaded important blood vessels or who are expected to have major bleeding during subsequent studies; 6. have a mental illness or can not cooperate with the treatment; 7. breastfeeding or pregnant women; 8. central, cavity lung squamous cell carcinoma, or non-small cell lung cancer patients with hemoptysis (>50mL/day); 9. There are contraindications to drugs.

Design outcomes

Primary

MeasureTime frame
Progression free survival;

Secondary

MeasureTime frame
Objective response rate;Overall survival;

Countries

China

Contacts

Public ContactHong Xiaohua

Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

hongxiaohua008@163.com+86 13886130223

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026