Regulation mechanism of TNF-alpha, IL-1beta, PGE2 and bradykinin on hyperalgesia in second eye cataract surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900023178

Enrollment

Unknown

Registered

2019-05-15

Start date

2019-06-30

Completion date

Unknown

Last updated

2019-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative hyperalgesia of the second eye after cataract surgery

Interventions

test group:Cataract surgery in two eyes at different times

Eligibility

Sex/Gender

All

Age

60 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) clear expression of mind; (2) both eyes intend to perform cataract surgery within a month; (3) the degree of cataract in both eyes is similar (to ensure that the operation time in both eyes is similar); (4) cataract surgery in both eyes is performed by the same experienced doctor.

Exclusion criteria

Exclusion criteria: (1) patients with intraoperative complications; (2) combined with diabetes or systemic immune disease; (3) long-term use of psychotropic drugs and non-steroidal anti-inflammatory drugs.

Design outcomes

Primary

Measure	Time frame
TNF-a;IL-1ß;	—

Secondary

Measure	Time frame
PGE2;bradykinin;	—

Countries

China

Contacts

Public ContactYang Ruibo

Tianjin Medical University Eye Hospital

yangruibo771@163.com+86 18802295667

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026