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Application of indocyanine green combined with near infrared fluorescence imaging in sentinel lymph node dissection for early endometrial cancer

Application of indocyanine green combined with near infrared fluorescence imaging in sentinel lymph node dissection for early endometrial cancer

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023161
Enrollment
Unknown
Registered
2019-05-14
Start date
2019-01-01
Completion date
Unknown
Last updated
2019-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometrial cancer

Interventions

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Sponsors

Zhejiang Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 and 70 years old woman; 2. Diagnostic curettage of endometrium suggests endometrioid adenocarcinoma; 3. Pelvic magnetic resonance imaging showed that the lesion was confined to the uterus; 4. There were no suspicious nodules in pelvic and abdominal magnetic resonance imaging (according to RECIST 1.1); 5. ECOG performance status 0-1 points; 6. Blood routine and biochemical examination: white blood cells (> 4000 cells/mm3), platelets (> 10,000/mm3), hemoglobin (> 8.0 gm/dL), serum creatinine (< 1.3 mg/dL), serum urea nitrogen (< 1.5 mg/dL); 7. Ability to sign informed consent and follow up.

Exclusion criteria

Exclusion criteria: 1. Pregnancy or lactation; 2. Double malignant tumors; 3. Received neoadjuvant chemotherapy and/or radiotherapy; 4. allergic reaction to blue dyes, isotopes or ICG; 5. Severe cardiopulmonary vascular diseases lead to intolerance of surgery. 6. Psychiatric patients; 7. Intraoperative sentinel lymph node status was not in accordance with the enrollment (i.e. one side was negative, one side was not visualized; lymph node invasion; no sentinel lymph node, other considerations were not suitable for enrollment).

Design outcomes

Primary

MeasureTime frame
disease-free survival;quality of life;overall survival;

Secondary

MeasureTime frame
Operative time;intraoperative bleeding;pelvic lymphocyst;infection;length of stay in the hospital;hospitalization costs;

Countries

China

Contacts

Public ContactZhu Tao

Zhejiang Cancer Hospital

zhutao@zjcc.org.cn+86 13858065156

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026