Breast cancer
Conditions
Interventions
Sponsors
The Third Hospital of Nanchang
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged =70 years, women; 2. HER2-positive advanced breast cancer patients diagnosed by pathology or histology; 3. The main viscera function of patients must be normal, and should meet the following requirements: 1) Echocardiography:LVEF=55%; 2) Twelve lead electrocardiogram:QTcF)< 470 msec; 4. Performance Status- Eastern Cooperative Oncology Group (ECOG) 0-1; 5. Signed and dated informed consent. Willingness and ability to comply with scheduled visits, treatment plans, laboratory tests, and other study procedure; 6. The researchers reckon that patients can benefit.
Exclusion criteria
Exclusion criteria: 1. Female patients during pregnancylactation or were positive after baseline pregnancy test; 2. The following several factors ,such as unable to swallow, chronic diarrhea and intestinal obstruction; 3. Was allergic to the study drug or any of its excipients, including HIV positive, or other acquired, congenital immunodeficiency disease, or a history of organ transplantation; 4. Any other condition that the investigator believes not suitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PFS; | — |
Secondary
| Measure | Time frame |
|---|---|
| OS;ORR;Incidence of brain metastasis;DCR; | — |
Countries
China
Contacts
Public ContactHong Wang
The Third Hospital of Nanchang
Outcome results
None listed