Postoperative Analgesia of Colorectal Surgery
Conditions
Interventions
Group N1:Use Nalmefene0.05µg/kg
Group N2:Use Nalmefene0.15µg/kg
Group N3:Use Nalmefene0.25µg/kg
Sponsors
The Second Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Open colorectal surgery lasting at least 2 h; 2. All had American Society of Anesthesiologists physical status I–III.
Exclusion criteria
Exclusion criteria: 1. Immediate extubation was not planned after surgery; 2. With chronic inflammatory disease including inflammatory bowel disease; 3. With a history of drug or alcohol abuse; 4. With contraindications to the self-administration of opioids (i.e., unable to understand the patient-controlled analge- sia [PCA] device); 5. With a history of psychiatric disorder; 6. With severe liver and kidney dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog scale; | — |
Countries
China
Contacts
Public ContactXiao Zhao Yang
The Second Hospital of Dalian Medical University
Outcome results
None listed