Individualized Preconditioning for ABO-Incompatible Living Donor Kidney Transplantation

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900023123

Enrollment

Unknown

Registered

2019-05-12

Start date

2019-06-03

Completion date

Unknown

Last updated

2019-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

end stage renal disease, kidney transplantation

Interventions

ABOi group:Individualized preconditioning, ABOi living donor kidney transplantation

ABOc group:ABOc living donor kidney transplantation

Eligibility

Sex/Gender

Male

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ESRD patients who are willing to receive living donor KTx; 2. All ABOi candidates had no suitable ABOc living donor; 3. Living donor/recipient aged 18-65 years; 4. Peak PRA<50%, no HLA DSA;

Exclusion criteria

Exclusion criteria: 1. extra-kidney organ transplant recipients; 2. CDC posititve; 3. active hepatitis; 4. active infection; 5. with history of cancer.

Design outcomes

Primary

Measure	Time frame
graft/patient survival, rejection, infection, graft function;	—

Secondary

Measure	Time frame
blood disorder, surgical complication, delayed graft function, malignancy, lab parameters (blood/urine tests, T cell population, B cell population, cytokines, immunoglobulin, complement, exosome miRNA etc);	—

Countries

China

Contacts

Public ContactTao Lin

Department of Urology/Institute of Urology, West China Hospital, Sichuan University

dr_taolin@163.com+86 13980031453

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026