High-flow nasal cannula oxygen versus non-invasive ventilation facemask for preoxygenation before intubation in pregnant patients: a randomised study.

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900023121

Enrollment

Unknown

Registered

2019-05-12

Start date

2019-05-27

Completion date

Unknown

Last updated

2019-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preoxygenation Before Intubation in pregnant patients

Interventions

non-invasive ventilation facemask:Traditional facemask pre-oxygenation was done breathing 100% oxygen with a tightly held facemask and a fresh gas flow of 10 l/min delivered via a circle system

High-flow nasal cannula oxygen:A flow of 60 l/min,37 Celsius heated and humidified 100% oxygen via a nasal cannula was delivered. The nasal cannula was left in place through the entire intubation proc

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1)ASA II-III; 2)aged 18-45 years; 3)BMI 18-35; 4)gestational age greater than 36 weeks, healthy singleton parturients ; 5)undergo elective cesarean section with general anesthesia.

Exclusion criteria

Exclusion criteria: 1)significant nasal pathology; 2)severe cardiac or respiratory disease, pre-eclampsia or sepsis.

Design outcomes

Primary

Measure	Time frame
PaO2 immediately after the intubation;	—

Secondary

Measure	Time frame
lowest SpO2 during intubation;: blood gas analysis of Umbilical vein;blood gas analysis of Umbilical Arterial;Arterial blood gas analysis of the parturients;FetO2 of the parturients immediately after the intubation;	—

Countries

china

Contacts

Public ContactShuangqiong Zhou

Shanghai First Maternity and Infant Hospital

zhousq@51mch.com+86 13916174158

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 17, 2026