Combination of Next-generation Sequencing and Hematology Methods optimizes Carrier Screening for Thalassemia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900023111

Enrollment

Unknown

Registered

2019-05-11

Start date

2019-05-01

Completion date

Unknown

Last updated

2019-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thalassemia

Interventions

Suspected population:be included into NGS group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Red cell indexes:microcytic hypochromic state without anemia or with mild anemia, serum ferritin normal;elevated HbA2 or elevated HbF.

Exclusion criteria

Exclusion criteria: moderate or severe anemia(beyond thalassemia carrier state); correction of microcytic hypochromic state post therapy with iron agent.

Design outcomes

Primary

Measure	Time frame
thalassemia genetic mutation;	—

Countries

China

Contacts

Public ContactLiu Li

Dongguan Houjie Hospital

doctor769@126.com+86 13712070258

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026