Clinical evaluation of multipulse 1064nm Nd: YAG laser combined with chemical nail dissolution in the treatment of onychomycosis

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900023103

Enrollment

Unknown

Registered

2019-05-11

Start date

2019-05-15

Completion date

Unknown

Last updated

2019-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Onychomycosis

Interventions

combination group:1064nm Nd: YAG laser combined with chemical nail dissolution

laser group:1064nm Nd :YAG laser

chemical nail dissolution group:chemical nail dissolution

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Patients with onychomycosis confiremed by history, clinical manifestations and laboratory results; (2) Fungal direct microscopy was positive and (or) fungal culture was positive; (3) 18-65 years old, male or female; (4) Women of childbearing age take effective contraceptive measures during the study period.

Exclusion criteria

Exclusion criteria: (1) Local combination of paronychia, severe bacterial infection or other skin diseases which may interfere with the diagnosis and treatment; (2) Patients with serious heart, liver, kidney disease, patients with diabetes and mental diseases; (3) Systemic use of glucocorticoid or immunosuppressant within 3 months; (4) Systemic use of antifungals within 6 months or topical use of antifungals within 1 month; (5) Pregnant and breast-feeding women; (6) Continuous or semi-continuous nail discoloration.

Design outcomes

Primary

Measure	Time frame
clinical efficacy rate;	—

Countries

China

Contacts

Public ContactYang Lianjuan

Shanghai Dermatology Hospital

zhy52808290@qq.com+86 18017336852

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026