Migraine anxiety/depression
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The diagnosis of migraine conforms to the diagnostic criterion of The International Classification of Headache Disorders, 2nd edition (ICHD- II) of the International Headache Society; 2. The intensity of headache is beyond moderate, Headache Impact Test-6 (HIT-6), score=50; 3. HAMD score=8; 4. Aged 18 to 65 years old; 5. Migraine prevention medications are not applied within the recent 8 weeks; 6. Participation is voluntary with informed consent signed. Patients who conform to all the 6 above mentioned prerequisites can be included into the study.
Exclusion criteria
Exclusion criteria: 1. secondary headache as epilepsy, cerebrovascular disease and intracranial space-occupying lesions; 2. Drug and alcohol abuse or drug abuse; 3. Suicide attempts and behavior; 4. Bipolar disorder or schizophrenia; 5. Serious internal medical problems; 6. dementia; 7. Both written and oral abnormal communication; 8. Women during pregnancy; 9. Drug treatment for other chronic pain symptoms. In either item, shall be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ERP P300;headache diary;HAMD;HAMA;HIT-6; | — |
Countries
China
Contacts
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences