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The feasibility of end-inspiratory or end-expiratory occlusion to predict fluid responsiveness for elder septic patients

The feasibility of end-inspiratory or end-expiratory occlusion to predict fluid responsiveness for elder septic patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023090
Enrollment
Unknown
Registered
2019-05-10
Start date
2015-02-01
Completion date
Unknown
Last updated
2019-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

positive fluid responsiveness:end-inspiratory/end-expiratory occlusio/fluid challeng
negative fluid responsiveness:end-inspiratory/end-expiratory occlusio/fluid challeng

Sponsors

Hangzhou Red Cross Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. aged older than 65 years; 2. the patient meets the diagnostic criteria of the 2016 International Sepsis Guidelines; patients need fluid resuscitation, at least one of the following tissue hypoperfusion: (1) systolic blood pressure (SBP) 100 times/min; (3) lactic acid>2mmol/L; 4 urine volume <0.5ml.kg-1.min-1.h -1; skin spots. 3. All patients' ventilators are set to pressure controlled ventilation mode.

Exclusion criteria

Exclusion criteria: (1) 15 seconds of apnea intolerance, excessive spontaneous breathing; (2) malignant arrhythmia (ventricular tachycardia, ventricular fibrillation) and severe acute left (CI <2.0 L/min/m2) or right ventricular dysfunction; (3) Trans-thoracic echocardiography.

Design outcomes

Primary

MeasureTime frame
CI, SVI;LVOT-VTI/Vmax;—

Secondary

MeasureTime frame
HR, NBP;—

Countries

China

Contacts

Public ContactJing Sun

Hangzhou Red Cross Hospital

sunjcross@zcmu.edu.cn+86 057156108423

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026