Effects of low-dose dobutamine on cerebral oxygen saturation and cognitive dysfunction after one-lung ventilation

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900023085

Enrollment

Unknown

Registered

2019-05-10

Start date

2019-05-08

Completion date

Unknown

Last updated

2019-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary nodule

Interventions

observation group:Dobutamine

control group:Normal saline

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Aged > 18 years, ASA grade I-III, one-lung ventilation (OLV) time > 45 minutes.

Exclusion criteria

Exclusion criteria: Anemia or intraoperative bleeding more than 400 ml, severe impairment of pulmonary function, forced expiratory volume/predicted value less than 50% in the first second, severe cardiovascular disease, arrhythmia, cerebrovascular disease, hyperthyroidism and other patients, severe liver and kidney dysfunction, Alzheimer's disease and history of mental illness, preoperative Mini-Mental State Assessment Scale (MMSE) score less than 24 points; Psychotropic drugs; obvious stenosis or malformation of carotid or vertebral arteries; asthma or chronic obstructive pulmonary disease.

Design outcomes

Primary

Measure	Time frame
rScO2;	—

Countries

China

Contacts

Public ContactPing Fang

Li Huili Hospital, Ningbo Medical Center, Zhejiang Province

549934608@qq.com+86 13989309825

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026