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The relationship between intestinal colonization of carbapenems resistant enterobacteriaceae (CRE) screening and pathogen infection

The relationship between intestinal colonization of carbapenems resistant enterobacteriaceae (CRE) screening and pathogen infection

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023076
Enrollment
Unknown
Registered
2019-05-10
Start date
2018-01-01
Completion date
Unknown
Last updated
2019-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CRE infection

Interventions

Carry CRE group:none

Sponsors

The Second Affiliated Hospital of Kunming Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
100 Years to No maximum

Inclusion criteria

Inclusion criteria: According to the research of Martirosov DM et al. in Emerging trends in epidemiology and management of diseases caused by carbapenem-resistant Enterobacteriaceae, the intensive care unit is the high-risk department of carbapenems resistant Enterobacteriaceae (CRE) infection: The literature review showed that the infection rate of carbapenems resistant enterobacteriaceae (CRE) in hospital intensive care units in some parts of the United States ranged from 1.5% to 8.7%, while that in non-icus ranged from 0.9% to 4.9%. Therefore, no bacterial infection occurred in the emergency critical care department and critical care department of the second affiliated hospital of kunming medical university, regardless of age or gender. The investigator informed the patients and their families of the purpose, risks and benefits of the study, and obtained the informed consent signed by the patients or their families. According to the study of the rapid spread of carbapenem-resistant Enterobacteriaceae published in Drug Resistance Updates by Potter RF et al., the CRE colonization rate of the intestinal tract was 10.90% significantly higher than that of other parts. Enterobacteriaceae bacteria, such as klebsiella pneumoniae, escherichia coli, enterobacter cloacae, citrobacter forschner and so on, are common colonizing bacteria in the digestive system. Therefore, feces were collected and inoculated within 48 hours after patients were transferred to ICU or admitted to hospital. Thereafter, patients with suspected bacterial infection were inoculated with blood or secretion specimens collected before antibiotic administration in accordance with the ACCP/SCCM consensus meeting and clinical manifestations.

Exclusion criteria

Exclusion criteria: No CRE was detected when patients to stay in ICU.

Design outcomes

Primary

MeasureTime frame
Carry CRE;

Secondary

MeasureTime frame
white blood cell;PCT;blood pressure;

Countries

China

Contacts

Public ContactLu Yang
ylcoolly@hotmail.com+86 15987140239

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026