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Effect of CagA protein expressed by Helicobacter pylori on intestinal flora of functional dyspepsia

Effect of CagA protein expressed by Helicobacter pylori on intestinal flora of functional dyspepsia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023054
Enrollment
Unknown
Registered
2019-05-09
Start date
2019-06-01
Completion date
Unknown
Last updated
2019-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional dyspepsia

Interventions

functional dyspepsia group:14 days quadruple anti-Hp program
Healthy people group:None

Sponsors

Affiliated Hospital of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: ? Due to various dyspepsia symptoms, from June 2019 to December 2019, I was admitted to the Department of Gastroenterology in our hospital. The symptoms mainly include upper abdominal pain, stomach burning, postprandial discomfort, early satiety and bloating, heartburn, belching, nausea, etc. ; ? Volunteer to participate in this study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: ? Age is less than or equal to 18 years old; ? Gigestive tract organic lesions, including active and scar ulcers, erosive esophagitis, Barrett's esophagitis, erosive gastritis, atrophic gastritis, malignant tumors; ? Combined with severe systemic diseases, including malignant tumors in any part, diabetes, advanced chronic kidney disease, cirrhosis; ? History of abdominal surgery; ? Have bleeding tendency or are using anticoagulant; ? Long-term use of aspirin, PPI preparations and other drugs (excluding other NSAIDS, antibiotics); ? Abdominal B-ultrasound or CT examination, laboratory examination diagnosed as liver, gallbladder, pancreas and other organic diseases; ? Metabolic diseases.

Design outcomes

Primary

MeasureTime frame
Fecal flora;

Countries

China

Contacts

Public ContactWangping Meng

Affiliated Hospital of Southwest Medical University

591870121@qq.com+86 15883012566

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026