Alveolar bone defect
Conditions
Interventions
Experimental group:Implant bone material and membrane
Control group:Implant bone material and membrane
Sponsors
West China Stomatological Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years male or female patients; 2. A single tooth with a reference to the adjacent tooth is required for bone grafting; 3. There is bone defect in the alveolar bone wall, and the vertical height of the bone wall with the largest bone defect is =5mm. It contains: 1) normal tooth extraction; 2) or the third impacted molar needs to be removed, and the distal bone defect of the adjacent tooth exceeds the root of the tooth. Patients with two-thirds or more of the length; 3) or a patient with a single tooth cyst; 4. Patients volunteered to participate in clinical trials, signed informed consent, and were able to cooperate with clinical follow-up.
Exclusion criteria
Exclusion criteria: 1. Participated in other clinical trials within 3 months prior to the start of the trial; 2. Various bone defects caused by invasive and malignant bone tumors; 3. Patients who may have affected or promoted the treatment of bone metabolism medications are being treated in the past 3 months; 4. Active infectious lesions, various bone defects produced during the active period of metabolic bone disease; 5. Patients with severe heart, liver and kidney dysfunction are defined as: Heart function: Level II and above; (1) ALT, AST> 2 times the upper limit of normal value; (2) serum creatinine> upper limit of normal value; 6. Patients with poor control of diabetes (drug-controlled fasting blood glucose is still = 8.0mmol / L); 7. Mental disorders, inactivity and autonomy; 8. Patients with allergic constitution; 9. Pregnant or lactating women and those with a pregnancy plan within six months; 10. Various subjects who can cause artifacts in the oral examination of the operation area, such as metal dentures, porcelain teeth, etc.; 11. The doctor judges other circumstances in which he or she cannot participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Combined bone graft after 180 days of imaging changes after alveolar bone defect repair; | — |
Secondary
| Measure | Time frame |
|---|---|
| Whether the test film is damaged or not, whether the filling has overflowed;Evaluation of clinical surgical incision healing;Rejection reaction;the variety of bone metabolism;Post-filling symptoms;The sign of bone infection; | — |
Countries
China
Contacts
Public ContactPan Jian
West China Hospital of Stomatology, Sichuan University
Outcome results
None listed