Coronary heart disease (CHD)
Conditions
Sponsors
The First Affiliated Hospital of He'nan University of CM
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. The patients with acute anterior myocardial infarction within 10 days, underwent emergency PCI, or underwent PCI after emergency thrombolytic therapy, or received elective PCI within 10 days; 2. The patients meet the syndrome differentiation standard of TCM with Deficient Qi and Yin combined blood stasis; 3. Aged 18 to 75 years, both men and women; 4. Sign the informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1. The patients with Multiple coronary artery branches lesions didnt receive elective PCI within 10 days; 2. Acute myocardial infarction with severe complications, such as acute heart failure, cardiogenic shock(conventional treatment cannot correct), or mechanical complication; 3. Acute myocardial infarction with heart failure, Killip classification III or IV; 4. Chronic heart failure or old anterior myocardial infarction in the past medical history; 5. Combined with other diseases, such as cardiomyopathy, rheumatic heart disease, valvular heart disease (Severe stenosis/incomplete closure), arrhythmia (persistent atrial fibrillation/atrial flutter, third degree a-v block, sick sinus syndrome, after implantation of pacemaker) hyperthyroidism, cardiac tamponade, pulmonary arterial hypertensionacute paroxysmal asthma/COPD, severe infection , and so on; 6. Patients with severe liver and kidney function impairment (ALT, AST or TBIL>3 times the upper limit of normal reference value, or Cr >=3mg/dL or eGFR=60ml/min1.73m2); and with severe primary diseases or mental diseases such as hematopoietic system; 7. Patients with malignant tumor; 8. Allergic constitution or allergy to multiple drug or food, allergy to known components of the study drugs; 9. Cannot take care of themselves and cannot receive oral drug; 10. Participated in other drug clinical trials within 1 month; 11. Suspecting or ensuring with a history of substance abuse alcohol or drug abuse; 12. Pregnant or lactating women, or planned pregnancy; 13. According to the judgment of the researcher, the subject is not suitable for involving.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| left ventricular end-diastolic volume index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Chinese medicine symptom complex score;Echocardiography;six-minute walk test;Seattle angina scale score;cardiac magnetic resonance imagingCMRI;biological indicator;NT-proBNP;Ambulatory ECG;Cardiovascular related deaths;Cardiovascular related hospitalization;Revascularization; | — |
Countries
China
Contacts
Public ContactWang Yongxia
The First Affiliated Hospital of He'nan University of CM
Outcome results
None listed