temporomandibular arthritis
Conditions
Interventions
experimental group :1 ml PRP was injected into the superior cavity of the affected temporomandibular joint. The total course of treatment included 2 injections, with an interval of 2 weeks (14 days)
control group:1 ml sodium hyaluronate was injected into the upper cavity of the affected temporomandibular joint. The total course of treatment included two injections, with an interval of 2 weeks (14
Sponsors
Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Subjects: Temporomandibular Osteoarthritis (TMJ-OA) patients with TMD Diagnostic Classification III B (arthralgia + articular frictional sounds or imaging changes) Aged 18-60 years; Men and women are not limited; Outpatient patients; CBCT confirmed TMD-OA patients with imaging changes before admission; Sign informed consent.
Exclusion criteria
Exclusion criteria: Other clinical trials were conducted within 4 weeks before the start of this study; Patients who underwent joint lavage or intra-articular injection within 2 weeks before the start of this study; Non-steroidal anti-inflammatory drugs were administered within one week before treatment; Septicemia, severe thrombocytopenia, platelet dysfunction; Infection of articular region; Previous TMJ surgery for patients; Patients with neurological diseases, immune system diseases, tumors and other attending physicians who do not consider them suitable for inclusion in the study; Cognitive impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficiency of pain improvement; | — |
Secondary
| Measure | Time frame |
|---|---|
| Maximum opening and mandibular movement;clicking of mandibular joints;CBCT Imaging;Activity of daily living; | — |
Countries
China
Contacts
Public ContactXu Lili
Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Outcome results
None listed