Laparoscopic cholecystectomy
Conditions
Interventions
group OBA:Remifentanil
group OFA:Dexmedetomidine + Lidocaine+Esketamine
Sponsors
The Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients were scheduled for elective laparoscopic cholecystectomy through 3 holes under general anesthesia.
Exclusion criteria
Exclusion criteria: Patients aged 65 years, with a body mass index (BMI) = 30 kg/m2, hepatic or renal disease, coagulopathy, history of alcohol or drug abuse, American Society of Anesthesiologists (ASA) physical status = III, basal heart rate (HR) = 50 beats/min, pregnant patients, patients with a past medical history of chronic pain, patients at risk for taking NSAIDs, those with allergies to related medication, and patients with communication disorders were all excluded from our study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The requirement for analgesics;postoperative pain level of visual analogue scale (VAS) at 2 hrs (T4), 8 hrs (T5), and 24 hrs (T6) after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| time of LMA removed ;recovery time of orientation;time to unassisted walking;sleep quality;time to first flatus;incidence of PONV;Global Satisfaction Score; | — |
Countries
China
Contacts
Public ContactYu Jun-Ma
The Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei)
Outcome results
None listed