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A prospective, randomized, controlled trial for mirilone for controlled low central venous pressure in hepatectomy

A prospective, randomized, controlled trial for mirilone for controlled low central venous pressure in hepatectomy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900022989
Enrollment
Unknown
Registered
2019-05-06
Start date
2019-05-13
Completion date
Unknown
Last updated
2019-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatectomy

Interventions

Group 1:R-L ml/kg/h + lasix 10mg/time
Group 2:glycerin 0.1-0.6ug/kg/min
Group 3:mirilone0.5ug/kg/min

Sponsors

the First Affiliated Hospital of Sun Yatsen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. aged 18 to 85 years, both male and female; 2. ASA 1~2, NYHA class 1; 3. elective hepatetomy.

Exclusion criteria

Exclusion criteria: 1. Hb child B class for liver function, renal insufuciency (BUN>9mmol/L, cr>178umol/L); 5. BMI>30; 6. Allergic to milrinone or nitroglycerin.

Design outcomes

Primary

MeasureTime frame
cardiac output;stroke volume variation;blood loss;—

Secondary

MeasureTime frame
infused fluid volume;urine volume;consumption of vasoactives;—

Countries

China

Contacts

Public ContactYang Peng

Anesthesiology Department, the First Affiliated Hospital of Sun Yatsen University

ypsums@126.com+86 13570291442

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026