peritoneal cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Preoperative examination showed no liver or lung metastasis or obvious retroperitoneal lymph node metastasis in patients with peritoneal carcinoma.
Exclusion criteria
Exclusion criteria: Preoperative complicated with severe systemic disease, can not tolerate surgery; Pregnant women with pain syndrome who have clotting disorders; Patients treated with immunomodulatory drugs preoperatively and postoperatively (e.g., blood diseases after organ transplantation); Patients taking antioxidant therapy preoperatively and postoperatively;People suffering from mental disorders (e.g., alzheimer's disease, anxiety disorders); Hearing impairment;The exclusion criteria for patients who are unwilling to cooperate with the researchers during the surgery is that the surgeon makes the decision not to perform the surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rest VAS pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| cough VAS score;Prince-Henry score;Ramsay score;Postoperative sufentanil dosage;Number of PCA presses;Postoperative complications;VAS score;Serum prostaglandin E2 levels immediately after intubation;Serum myocardial substance P levels immediately after intubation;Serum TNF-a levels immediately after intubation;Serum Interleukin -1ß levels immediately after intubation;Serum Interleukin -6levels immediately after intubation;Serum malondialdehyde levels immediately after intubation;Serum levels of late oxidized protein products immediately after intubation;Serum ros levels immediately after intubation; | — |
Countries
China
Contacts
Anesthesiology Department, Beijing Shijitan Hospital, Capital Medical University