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Effects of transversus abdominis plane blockon acute and chronic pain after CRS+HIPEC

Effects of transversus abdominis plane blockon acute and chronic pain after CRS+HIPEC

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900022984
Enrollment
Unknown
Registered
2019-05-06
Start date
2019-05-20
Completion date
Unknown
Last updated
2019-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

peritoneal cancer

Interventions

Experimental group:Ultrasound-guided transverse abdominis
Control group:none

Sponsors

Anesthesiology Department, Beijing Shijitan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Preoperative examination showed no liver or lung metastasis or obvious retroperitoneal lymph node metastasis in patients with peritoneal carcinoma.

Exclusion criteria

Exclusion criteria: Preoperative complicated with severe systemic disease, can not tolerate surgery; Pregnant women with pain syndrome who have clotting disorders; Patients treated with immunomodulatory drugs preoperatively and postoperatively (e.g., blood diseases after organ transplantation); Patients taking antioxidant therapy preoperatively and postoperatively;People suffering from mental disorders (e.g., alzheimer's disease, anxiety disorders); Hearing impairment;The exclusion criteria for patients who are unwilling to cooperate with the researchers during the surgery is that the surgeon makes the decision not to perform the surgery

Design outcomes

Primary

MeasureTime frame
rest VAS pain score;

Secondary

MeasureTime frame
cough VAS score;Prince-Henry score;Ramsay score;Postoperative sufentanil dosage;Number of PCA presses;Postoperative complications;VAS score;Serum prostaglandin E2 levels immediately after intubation;Serum myocardial substance P levels immediately after intubation;Serum TNF-a levels immediately after intubation;Serum Interleukin -1ß levels immediately after intubation;Serum Interleukin -6levels immediately after intubation;Serum malondialdehyde levels immediately after intubation;Serum levels of late oxidized protein products immediately after intubation;Serum ros levels immediately after intubation;

Countries

China

Contacts

Public ContactTianzuo Li

Anesthesiology Department, Beijing Shijitan Hospital, Capital Medical University

Sy1610147@163.com+86 15330269996

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026