acute myocardial infarction
Conditions
Interventions
Experimental Group:Combined therapy of N-acetylcysteine and local ischemic postconditioning
Control group:5% dextrose
Sponsors
Department of Cardiology, Fujian Medical University Union Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 120 Years
Inclusion criteria
Inclusion criteria: 1. Chest pain = 12 hours; 2. Aged = 18 years; 3. STEMI (ST segment elevation in two or more adjacent leads of ECG: V2-V3 lead = 0.2mV in male or female = 0.15mV and/or other leads = 0.1mV); 4. Consent to emergency PCI treatment.
Exclusion criteria
Exclusion criteria: 1. Previous coronary artery bypass grafting; 2. Previous myocardial infarction; 3. Received thrombolytic therapy before coronary angiography; 4. Left main coronary artery disease requires coronary artery bypass grafting (CABG) or severe heart failure requires mechanical ventilation or intra-aortic ballon pump (IABP) implantation; 5. Life expectancy due to non-cardiac diseases is less than 1 year; 6. Patients who are participating in other clinical trials; 7. Researchers consider that patients are not eligible for the clinical trials for other factors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| myocardial infarct size; | — |
Secondary
| Measure | Time frame |
|---|---|
| net adverse clinical events;TIMI flow after PCI; | — |
Countries
China
Contacts
Public ContactChen Lianglong
Fujian Medical University Union Hospital
Outcome results
None listed