in nonhypoxic patients undergoing surgery
Conditions
Interventions
Case series:Different Inspiratory Oxygen Fraction
Sponsors
Department of Anesthesiology, Zhejiang Provincial People's Hospital (People's Hospital of Hangzhou Medicine College)
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. One hundred and twenty patients scheduled for elective surgery under general anesthesia will be included elective surgery; 2. aged =18 years; 3. ASA I-II; 4. body mass index (BMI) 18-30 kg/m2; 5. estimated operative time = 2.5 hours; 6. need radial artery puncture and central venous catheterization; 7. preoperative PaO2 > 60 mmHg.
Exclusion criteria
Exclusion criteria: 1. emergency surgery or history of previous lung surgery; 2. history of mechanical ventilation within the 2 weeks before recruitment;] 3. non–invasive ventilation or oxygen therapy at home; 4. acute respiratory failure (pneumonia, acute lung injury or acute respiratory distress syndrome); 5. history of chronic obstructive pulmonary disease (COPD); 6. scheduled for thoracic surgery or with a history of thoracic surgery; 7. persistent hemodynamic instability or severe cardiac disease (New York Heart Association class III or IV, or persistent ventricular tachyarrhythmias, or acute coronary syndrome); 8. sepsis or septic shock, need renal replacement therapy (CRRT); 9. progressive neuromuscular illness; 10. pregnancy, participation in another study or refusal to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PaO2; | — |
Countries
China
Contacts
Public ContactZhen-feng ZHOU
Department of Anesthesiology, Zhejiang Provincial People,s Hospital (People,s Hospital of Hangzhou Medicine College)
Outcome results
None listed