Recurrent Spontaneous Abortion
Conditions
Interventions
Treatment-as-usual (TAU):Oral low-dose aspirin 75 mg/day plus folic acid 400 mcg/day for less than or equal to six menstrual cycles or if they conceived, throughout pregnancy with study drug discontin
MBSR:The standard MBSR program consists of 8 weekly sessions of around 2.5 h each. In addition to inclass mindfulness exercises, participants are encouraged to engage in home mindfulness practice (45
Sponsors
Shanxi Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Woman aged 20 to 40 years; 2. URSA diagnosis according to Expert consensus on diagnosis and treatment of recurrent abortion 2016; 3. Willing to have another pregnancy within half a year; 4. Written informed consent.
Exclusion criteria
Exclusion criteria: 1. Currently suffering fromserious physical illnesses such as autoimmune diseases, heart disease or chronic respiratory diseases; 2. Currently suffering from mental illness or having a history of mental illness; 3. Pregnant or no willingness to pregnant within six months; 4. Abnormal ovarian function: basal FSH> 15 IU/L or other situations that significantly affect fertility; 5. Patient or spouse refused to cooperate with the completion of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Pregnancy Rate;Live Birth Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Perceived Stress Scale;Self-rating Anxiety scale;Self-rating depression scale;serum cortisol;Th1/Th2/Th17/Treg cell number and proportion;cytokines IFN-?, IL-4, IL-17 and FoxP3; | — |
Countries
China
Contacts
Public ContactZhang Zhiping
Women Health Center & Chindren's Hospital, Shanxi Medical University
Outcome results
None listed