Breast Cancer
Conditions
Interventions
Sponsors
Southwest Hospital, Army Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years old; 2. histologically and/or cytologically confirmed breast cancer; 3. Initial treatment; no breast or axillary surgery before treatment; 4. Preoperative physical and auxiliary examination showed that the axillary fossa had no obvious structural abnormal swelling of the lymph nodes and no distant metastasis; 5. Patients must have the ability to understand and voluntarily sign informed consent; 6. ECOG physical status score is 0 to 2; 7. Subjects have no major organ dysfunction, laboratory test indicators must meet the following requirements: Hematology: white blood cells = 3.5 × 10^9/L, neutrophils = 2.0 × 10^9/L, platelet count = 100 × 10^9/L, hemoglobin = 95g/L; Liver function: serum bilirubin is less than 1.5 times the maximum normal value; ALT and AST are less than 1.5 times the maximum normal value. Renal function: creatinine clearance rate = 45mL / min; Heart function: Basically normal.
Exclusion criteria
Exclusion criteria: 1. patient had undergone surgery in the axillary region to destroy lymphatic drainage in this area; 2. Multi- or multi-focal breast cancer; 3. Axillary lymph node metastasis has been found clinically; 4. Patients with other system diseases or malignant tumors that cannot be operated ; 5. Breast cancer patients during pregnancy; 6. lactating breast cancer patients; 7. Researchers believe that other reasons are not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sentinel lymph node detection rate;Sensitivity;False negative rate;Local and systemic side effects;Axillary recurrence;Distant metastasis;Survival situation; | — |
Countries
China
Contacts
Public ContactXiaowei Qi
Southwest Hospital, Army Medical University
Outcome results
None listed