Laparoscopic radical gastric cancer
Conditions
Interventions
1:Low-pressure pneumoperitoneum+deep rocuronium-Induced neuromuscular blockade
2:standard-pressure pneumoperitoneum(12-15mmHg)+deep rocuronium-Induced neuromuscular blockade
3:standard-pressure pneumoperitoneum(12-15mmHg)+standard rocuronium-Induced neuromuscular blockade
Sponsors
Ningbo First Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Aged 60 years to 85 years; (2) The usual residence is less than 2500 meters above sea level; (3) Alternative radical laparoscopic gastric cancer.
Exclusion criteria
Exclusion criteria: (1) ASA IV or V or VI; (2) Severe blood system disease or coagulation dysfunction clearly diagnosed in clinical practice; (3) Patients with preoperative chemotherapy; (4) Patients with renal insufficiency(glomerular filtration rate & lt; 30 mL/min); (5) Patients with liver function impairment(AST, ALT is more than 1.5 times normal); (7) Known or suspected allergies to drugs used during anesthesia,(family) history of neuromuscular diseases,(family) history of malignant hyperthermia; The tumor has metastasized at a distance; (8) Can not cooperate with research for any reason, such as the following situations: language understanding, mental illness, etc.. (9) Taking other experimental drugs or participating in other clinical trials within 3 months before being selected for the study. (10) The researcher believes that it is not appropriate to include this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| L-SRS surgical condition score; | — |
Secondary
| Measure | Time frame |
|---|---|
| TNF-a?IL- 6 concentration;BP?HR?SPO2?TOFc??PTC value,SpHb,SPI value; | — |
Countries
China
Contacts
Public ContactChangshun Hang
Ningbo First Hospital
Outcome results
None listed