macronodular cirrhosis
Conditions
Interventions
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with chronic hepatitis B cirrhosis who meet the diagnostic criteria; 2.Hepatic regenerative nodules (> 3 mm) were detected by B-mode ultrasonography and MRI. 3.Age ranges from 18 to 65 years, gender is not limited. 4.Sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with cirrhosis caused by other hepatophilic virus infection or other pathogenic factors; (2) The presence or suspected presence of primary hepatocellular carcinoma lesions was detected by B-mode ultrasonography and MRI. (3) The patients with decompensated cirrhosis, such as those with Child-Pugh C grade > 12 points, had upper gastrointestinal bleeding, hepatic encephalopathy, intractable ascites, hemorrhagic tendency, hepatorenal syndrome and primary hepatocellular carcinoma in the past six months. (4) Patients with severe primary diseases of heart, kidney, lung, endocrine, blood, metabolism and gastrointestinal tract; or psychiatric patients. (5) Pregnant women or breast-feeding women who are willing to have children in the near future.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of primary liver cancer;Incidence and mortality of severe hepatitis;Incidence of upper gastrointestinal hemorrhage, hepatic encephalopathy and hepatorenal syndrome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Virological indicators;Liver function;CBC;Alpha fetoprotein;Ultrasound/MRI of Upper Abdomen;Fibroscan;TCM Syndrome Scale and Quality of Life Scale; | — |
Countries
China
Contacts
Public ContactGao Yueqiu
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed