Knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Repeated knee joint pain in the past 1 month; (2)X-ray films (standing position or load-bearing position) showed narrowing of joint space, subcartilage osteosclerosis and / or cystic degeneration, and formation of osteophyte at the edge of the joint; (3) Age = 50 years; (4) Morning stiffness time = 30 min; (5) there is bone friction sound (feeling) during the activity. Osteoarthritis of knee joint can be diagnosed by meeting the diagnostic criteria of 1 + (any 2 of 2, 3, 4 and 5).
Exclusion criteria
Exclusion criteria: (1) there was skin damage around the knee joint; (2) patients with history of knee surgery and severe trauma; (3) patients with secondary OA, complicated with rheumatoid arthritis, gouty arthritis, infectious arthritis and other joint diseases; (4) patients with diabetes mellitus, systemic infection, severe abnormal liver and kidney function, malignant tumor and other diseases; (5) the patients were treated with non-steroidal anti-inflammatory drugs and intra-articular injection in the past 3 months; (6) those who were allergic to drugs in this study; (7) pregnant or lactating women; (8) patients with mental disorder or cognitive dysfunction; (9) those who did not accept or could not adhere to the treatment plan of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PPT;Pain visual analog score;Chinese version of pain self-efficacy questionnaire; | — |
Countries
China
Contacts
Guanghua Hospital, Shanghai University of Chinese Medicine