thoracolumbar spinal operation
Conditions
Interventions
Group D:intratracheal dexmedetomidine
Group R:intratracheal ropivacaine
Group DR:intratracheal dexmedetomidine combined with ropivacaine
Sponsors
The First People's Hospital of Hefei, Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients to be scheduled for elective thoracolumbar spinal operation under general anesthesia
Exclusion criteria
Exclusion criteria: Patients with a BMI 30 kg/m2, heart rate (HR) <50 bpm at a pre-operativevisit, renal or hepatic disease, opioids or tranquilizersiffic usage (treat for more than 1 wk before the operation), a history of alcohol or drug abuse, ASA physical status III or greater, contraindications to any of the drugs used in the study, and pregnancy. Moreover,difficult airway or history of maxillofacial and neck surgery; chronic respiratory disease such as chronic obstructive pulmonary disease or asthma, recent respiratory tract infection, chronic cough, current smoking, anesthesia time more than 4 h, and delayed extubation (more than 1 h without extubation) because of adverse effect to experimental drugs, transferd to the Intensive Care Unit (ICU) with the tube were eliminated.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sore throat; | — |
Secondary
| Measure | Time frame |
|---|---|
| HR and MAP;analgesic drug consumption;First injection of Remifentanil; | — |
Countries
China
Contacts
Public ContactYu Junma
The First People's Hospital of Hefei, Anhui Medical University
Outcome results
None listed