Depression
Conditions
Interventions
Experimental group:msECT
Sponsors
Shenzhen Kangning Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Patient (18 21; 4) Patient was competent to provide informed consent; and 5) Patient was sufficiently fluent in Chinese to ensure valid responses to the neuropsychological tests.
Exclusion criteria
Exclusion criteria: 1) Failure to respond to earlier ECT; 2) ECT within the last six months; 3) Rapid-cycling or mixed-episode bipolar disorder; 4) Medication use incompatible with ECT treatment (such as lithium, benzodiazepine, antiepileptic drugs, etc.). Use of these drugs will be stopped at least 5 half-lives before the start of treatment; 5) Inability to follow the study protocol; 6) Unstable, serious comorbid medical condition (Parkinson’s disease, multiple sclerosis, stroke, alcohol use disorder, etc.) or history of epilepsy; 7) Intelligence quotient (IQ) = 70 tested by the Wechsler Adult Intelligence Scale 4th edition ; 8) = 9 years of education; 9) Pregnancy or women without adequate contraception; 10) Young Mania Rating Scale (YMRS) score [25] > 20.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD-24 score; | — |
Secondary
| Measure | Time frame |
|---|---|
| PANSS;cognitive function;social function; | — |
Countries
China
Contacts
Public ContactXin-hui Xie, Ying-jia Yang
Shenzhen Kangning Hospital
Outcome results
None listed