Effects of salbutamol aerosol on sevoflurane pharmarcodynamics and incidence of early postoperative pulmonary complications in patient with chronic pulmonary obstructive disease

Effects of salbutamol aerosol on sevoflurane pharmarcodynamics and incidence of early postoperative pulmonary complications in patient with chronic pulmonary obstructive disease: a randomized controlled study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900022899

Enrollment

Unknown

Registered

2019-04-30

Start date

2019-07-19

Completion date

Unknown

Last updated

2019-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease

Interventions

1:salbutamol aerosol

2:blank control reagent

Eligibility

Sex/Gender

All

Age

65 Years to 75 Years

Inclusion criteria

Inclusion criteria: ASA physical I-II, aged 65 to 75 yeats, long history of smoking, confirmed chronic bronchitis, emphysea and COPD; mild to imtermediate COPD based on preoperative lung function test, no upper respiratory tract infection 2 weeks before surgery. Excluding the exacerbation of COPD.

Exclusion criteria

Exclusion criteria: Allergic to salbutamol, alcohol and feron.Pulmonary hypertension; cardiac dysfunction or heart failure; refusal to participate; renal insufficiency BUN?10 mmol·L-1, Cr?1.5 mg·dl-1.

Design outcomes

Primary

Measure	Time frame
end-tidal concentration of sevoflurane;	—

Countries

China

Contacts

Public ContactJiang Zongming

Shaoxing People's Hospital

jiangzhejiang120@163.com+86 13515852725

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026