thoracoscopic lung surgery
Conditions
Interventions
Group 1:Intrapleural injection of 0.75% ropivacaine 15ml + dexmedetomidine 50ug 5ml
Group 2:Intrapleural injection of 0.75% ropivacaine 15ml + 0.9% sodium chloride injection 5ml
Sponsors
The First Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 68 Years
Inclusion criteria
Inclusion criteria: Selected as an ASA grade I to II, aged 18-68 years, elective thoracic surgery for thoracoscopic surgery.
Exclusion criteria
Exclusion criteria: 1. Allergic or contraindicated to amide local anesthetics, opioids, dexmedetomidine and other drug components; 2. Patients with a history of chronic pain; patients with severe central nervous system, liver and kidney dysfunction, severe heart failure, severe heart block, and severe ventricular dysfunction; 3. Patients with a history of dependence on alcohol and opioids; 4. Patients who used opioids for nearly a week; 5. Patients with digital analogue scale (NRS) and BMI 30 kg/m2 were not available.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the duration time of analgesic effect after pleural cavity injection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood concentration;the onset time of analgesic effect after pleural cavity injection;morphine consumption; | — |
Countries
China
Contacts
Public ContactXuzhong Xu
The First Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed