Patients undergoing elective general anesthesia
Conditions
Interventions
butorphanol group (B1, B2, B3):intravenous butorphanol
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Obese patients undergoing laparoscopic upper abdominal surgery; 2. Aged 18~60 years; 3. ASA I-II; 4. BMI 18-30; 5. The time of operation 2-4h; 6. Sign written informed consent and unwilling to abide by research protocols approved by the investigator.
Exclusion criteria
Exclusion criteria: 1. Pregnancy or breastfeeding; 2. Liver and kidney disease; 3. Hb<90g/L; 4. Preoperative severe impairment of respiratory function; 5. Pulmonary hypertension; 6. Heart failure, coronary heart disease, myocardial infarction; 7. Subjects has contraindication for butorphanol; 8. Patients with preoperative hypoxemia(SPO2<95%) 9. Subjects considered by the investigator to have any other factors not suitable for participation in the clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hypoxic frequency after extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Opioid dosages; | — |
Countries
China
Contacts
Public ContactLiu Su
Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed