Cognitive Decline and Alzheimer disease
Conditions
Interventions
Group 1:cognitive training
Group 3:music training
Group 4:cognitive training + transcranial direct current stimulation+exercise training
Group 5:music training+cognitive training+reminiscence
Sponsors
Institute of Psychology, Chinese Academy of Sciences
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria of MCI: 1. subjective complaints of memory loss above 6 months, preferably corroborated by an informant; 2. evidence of objective memory impairment confirmed by one standard deviation (SD) below the expected levels for age and education on the memory scale; 3. normal general cognitive functioning confirmed by MMSE scores (MMSE>24; or MoCA 21-26); 4. intact activities of daily life (ADL <16); 5. level 2 or level 3 on the global deterioration scale (GDS), clinical dementia rating scale, CDR=0.5; 6. Hachinski Ischemia Scale, HIS<=4; Inclusion criteria of mild dementia: 1. clinical dementia rating scale, CDR=1; 2. MMSE 19-23. Inclusion criteria of moderate dementia: 1. clinical dementia rating scale, CDR=2; 2. MMSE 10-18.
Exclusion criteria
Exclusion criteria: Currently with or history of significant medical, neurological, or psychiatric illness (such as depression and anxiety).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| global cognitive ability;memory;executive function;verbal ability;living quality; | — |
Countries
China
Contacts
Public ContactJuan Li
Outcome results
None listed