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Clinical observation for chemical neurolysis of thoracic sympathetic nerve block in the treatment of thoracic postherpetic neuralgia: a prospective randomized controlled clinical trial

Clinical observation for chemical neurolysis of thoracic sympathetic nerve block in the treatment of thoracic postherpetic neuralgia: a prospective randomized controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900022827
Enrollment
Unknown
Registered
2019-04-27
Start date
2019-05-06
Completion date
Unknown
Last updated
2019-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postherpetic neuralgia

Interventions

Sponsors

The First Affiliated Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Understand and voluntarily endorse informed consent; 2. Male or female and 18 years of age or older; 3. At least four months after the rash onset; 4. Pain (rash site) is located between Thoracic 3 to Thoracic 10; 5. Patients who experienced moderate to severe pain before enrollment: with an average daily pain score of ?4 (VAS?4) or daily pain outbreak of ?3 times; 6. Patients who can be able to follow the drug dose and the follow-up plan; 7. Patients who can objectively describe the symptoms, can take the initiative to cooperate, without any mental illness.

Exclusion criteria

Exclusion criteria: Subjects complying with any of the following exclusion criteria are not eligible to participate in this study: 1. Patients who have any objections to this trial; 2. Serious organ damage, such as CHF (congestive heart-failure), patients with clinical symptoms of coronary artery disease and arrhythmia uncontrollable by existing medicines, etc.; 3. MRI examination showed that patients were not suitable for thoracic sympathetic nerve block 4.Patients with allergic diseases, allergic constitution, drug allergic history (gabapentin, pregabalin, oxycodone-acetaminophen, local anesthetics, absolute alcohol;); 5.Severe systemic infection, Coagulation dysfunction; 6.Patients with psychiatric disease affecting assessments; 7.Patients with malignant tumor or with a history of malignant tumor. 8. Patients unable to follow the follow-up plan; 9. Patients in other clinical research at the same time; 10. The patients that researchers do not consider fit for the trial

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale/Score(VAS);

Secondary

MeasureTime frame
The Short Form (36) Health Survey;Dosage of analgesics;

Countries

China

Contacts

Public ContactTao Song

The First Affiliated Hospital of China Medical University

songtaocmu@163.com+8615840599900

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026