postherpetic neuralgia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Understand and voluntarily endorse informed consent; 2. Male or female and 18 years of age or older; 3. At least four months after the rash onset; 4. Pain (rash site) is located between Thoracic 3 to Thoracic 10; 5. Patients who experienced moderate to severe pain before enrollment: with an average daily pain score of ?4 (VAS?4) or daily pain outbreak of ?3 times; 6. Patients who can be able to follow the drug dose and the follow-up plan; 7. Patients who can objectively describe the symptoms, can take the initiative to cooperate, without any mental illness.
Exclusion criteria
Exclusion criteria: Subjects complying with any of the following exclusion criteria are not eligible to participate in this study: 1. Patients who have any objections to this trial; 2. Serious organ damage, such as CHF (congestive heart-failure), patients with clinical symptoms of coronary artery disease and arrhythmia uncontrollable by existing medicines, etc.; 3. MRI examination showed that patients were not suitable for thoracic sympathetic nerve block 4.Patients with allergic diseases, allergic constitution, drug allergic history (gabapentin, pregabalin, oxycodone-acetaminophen, local anesthetics, absolute alcohol;); 5.Severe systemic infection, Coagulation dysfunction; 6.Patients with psychiatric disease affecting assessments; 7.Patients with malignant tumor or with a history of malignant tumor. 8. Patients unable to follow the follow-up plan; 9. Patients in other clinical research at the same time; 10. The patients that researchers do not consider fit for the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale/Score(VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| The Short Form (36) Health Survey;Dosage of analgesics; | — |
Countries
China
Contacts
The First Affiliated Hospital of China Medical University