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Evaluation of 3-day Azithromycin, 5 days Cefaclor in Comparison with 10-day Amoxicillin for Treatment of Tonsillitis in Children

Evaluation of 3-day Azithromycin, 5 days Cefaclor in Comparison with 10-day Amoxicillin for Treatment of Tonsillitis in Children

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900022792
Enrollment
Unknown
Registered
2019-04-26
Start date
2016-11-01
Completion date
Unknown
Last updated
2019-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tonsillitis

Interventions

Azithromycin:10 mg/?????/??,????
Cefaclor:20 mg/kg/day three times a day for 5 days
Amoxicillin:30 mg/kg/day in three divided doses for 10 days

Sponsors

Li Peng
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 12 Years

Inclusion criteria

Inclusion criteria: children with signs and symptoms of tonsillitis of both sexes, aged between 2 to 12 years were recruited. The children were diagnosed of tonsillitis by the presence of a sore throat and / or a swollen, hyperemic or suppurated tonsil and/or visible secretions or erythema of tonsil, and / or with fever.

Exclusion criteria

Exclusion criteria: 1) history of hypersensitivity to macrolides or beta-lactams; 2) patients with a medication history of corticoids or montelukast; 3) patients had already received antibiotic treatment up to 7 days before enrollment; 4) patients have undergone tonsillectomy, adenoidectomy or a previous reduction of tonsils; 5) patients had a history of rheumatic fever, or had a peritonsillar abscess; 6) patients with potential viral infection or other underlying severe diseases.

Design outcomes

Primary

MeasureTime frame
microbiologic results;

Countries

China

Contacts

Public ContactLi Peng

Children's Hospital of Nanjing Medical University

etyylipeng@163.com+86 18851154288

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026