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Effects of goal-directed fluid therapy on postoperative outcomes in patients undergoing laparoscopic colorectal surgery in different levels of systemic vascular resistance after general anesthesia

Effects of goal--directed fluid therapy on postoperative outcomes in patients undergoing laparoscopic colorectal surgery in different levels of systemic vascular resistance after general anesthesia

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900022775
Enrollment
Unknown
Registered
2019-04-25
Start date
2019-05-01
Completion date
Unknown
Last updated
2019-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

1:Norepinephrine + GDFT
2:GDFT

Sponsors

Shanxi Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: Our confirmed fitting line of adult patients undergoing elective laparoscopic colorectal cancer surgery, ASA I to II level, aged 50 to 70 years, preoperative red blood cell pressure product > 30%, hemoglobin > 100 g/L, albumin > 25 g/L, body mass index (BMI) of 18 to 28 kg/m2, the patient and family to know and sign the informed consent.

Exclusion criteria

Exclusion criteria: Patients with preoperative gastrointestinal dysfunction; Contraindications of deep vein puncture, radial artery puncture and laparoscopic surgery; Concomitant severe heart valve dysfunction, severe arrhythmia, heart failure; Patients with severe liver disease (liver enzyme > normal value 50%); Patients with clotting dysfunction or who have recently taken drugs affecting clotting function; Patients with pulmonary infection, acute or chronic tuberculosis or severe chronic obstructive pulmonary disease are treated with drugs that affect clotting function; Patients who need transfusions of allogeneic blood during the operation; Patients with acute and chronic renal disease. Shedding cases: serious complications occurred during the operation; Intraoperative NBP of patients with SVV reaching the standard was still lower than the baseline blood pressure, and other positive inotropic drugs should be given.

Design outcomes

Primary

MeasureTime frame
postoperative complications;

Countries

China

Contacts

Public ContactYouzhang Liu

Shanxi Provincial People's Hospital

lyzh98139@163.com+86 15834058340

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026