Knee osteoarthritis
Conditions
Interventions
Experimental group:Patients undergo total knee arthroplasty with kinematic alignment
Control group:Patients undergo total knee arthroplasty with mechanical alignment
Sponsors
Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Aged =18 years. 2) The patient have to be Chinese citizen and can be follow-up visited. 3) Undertake total knee arthroplasty. 4) Informed consent is available. 5) The patients can cooperate with the study. 6) Diagnosed with knee osteoarthritis. 7) The cognitive status of patients is good. 8) The patient can only undergo total knee arthroplasty unilaterally in this study.
Exclusion criteria
Exclusion criteria: 1) The affected side of the knee has accepted another surgery before. 2) An extra-articular deformity was found. 3) With the diseases the researchers think would affect the study. 4) With metabolic disease the researchers think would have a negative effect on the study. 5) With neurogenic disease the researchers think would have a negative effect on the study. 6) With mental disease the researchers think would have a negative effect on the study. 7) The patients are undergoing another study. 8) Allergy to the prosthesis. 9) hemoglobin2 times of the normal upper limit, ESR>2 times of the normal upper limit and with a aoagulation abnormality.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee Society Score;Knee Injury&Osteoarthritis Outcone;Oxford knee seessment;Forgotten Joint Score-12;SF-36;The western Ontario and McMaster university of orthopedic index;Visual Analogue Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| CT;MRI;Gait analysis;Equilibrium function;Isokinetic muscle strength; | — |
Countries
China
Contacts
Public ContactHu Yihe
Department of orthopedics, Xiangya Hospital of Central South University
Outcome results
None listed