sleep apnea, lung cancer
Conditions
Interventions
A group: non-OSA and non-lung cancer
B group: OSA without lung caner
C group: Lung cancer without OSA
D group: Lung cancer combined with OSA.:no intervention
Sponsors
Beijing Chaoyang Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Aged 18~75 years; ? Newly-diagnosed advanced non-small cell lung cancer, available tumour tissue for testing; ? The controls will be recruited from those admit to sleep medical center, age, gender and body weight matched with lung caner patients.
Exclusion criteria
Exclusion criteria: ? With symptomatic brain metastasis, mentally or breath malfunction. ? Accompany with other tumor. ? Already accept radiotherapy or chemotherapy. ? Patients who have been diagnosed with sleep disordered breathing and relevant treatment. ? Combined with decompensated organ dysfunction (respiratory failure, heart failure, renal failure, etc.), psychological?illness. ? Need long-term oxygen therapy or use mechanical ventilation. ? Pregnant and lactating women. ? Combine with infectious diseases, such as active tuberculosis. ? Can not be treated or follow-up on time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival time;HIF-1a;VEGF; | — |
Secondary
| Measure | Time frame |
|---|---|
| progression-free survival;disease control rate;objective response rate;SF-36 life quality; | — |
Countries
China
Contacts
Public ContactZhang Dongmei
Beijing Chaoyang Hospital, Capital Medical University
Outcome results
None listed