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Management of brain metastases in tyrosine kinase inhibitor-naive epidermal growth factor receptor-mutant non-small-cell lung cancer from the perspective of long-term radiation brain damage: a case records based retrospective study

Management of brain metastases in tyrosine kinase inhibitor-naive epidermal growth factor receptor-mutant non-small-cell lung cancer from the perspective of long-term radiation brain damage: a case records based retrospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900022750
Enrollment
Unknown
Registered
2019-04-24
Start date
2019-04-24
Completion date
Unknown
Last updated
2019-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Case group versus control group:None

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with brain primary or metastatic tumors; 2. SRS history of intracranial lesions; 3. Pathological puncture or imaging diagnosis of brain radiation necrosis.

Exclusion criteria

Exclusion criteria: 1. the follow-up time was <10 months for patients with no brain necrosis after stereotactic radiotherapy; 2. the local lesions could not be further characterized during their surgery after SRS.

Design outcomes

Primary

MeasureTime frame
CRN;

Countries

China

Contacts

Public ContactZhuang Hongqing

Peking University Third Hospital

yiduzhengmu@163.com+86 13051776232

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026