Total knee arthroplasty
Conditions
Interventions
Sponsors
Guanghua Hospital, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) The primary unilateral total knee arthroplasty is required for the end stage of primary OA; 2) Aged 60-80 years old; 3) perioperative patients receiving tranexamic acid antifibrinolytic therapy; 4) Preoperative hemoglobin, normal coagulation function.
Exclusion criteria
Exclusion criteria: 1) Patients with secondary osteoarthritis other than primary knee osteoarthritis or rheumatoid arthritis (eg post-traumatic osteoarthritis, gouty osteoarthritis, hemophilic osteoarthritis, tuberculosis, Arthritis, ankylosing spondylitis, etc.); 2) Primary OA or RA requiring bilateral total knee arthroplasty; 3) suffering from severe cardiovascular diseases (such as myocardial infarction, atrial fibrillation, angina pectoris, heart failure, etc.), cerebrovascular diseases (cerebral infarction, cerebral hemorrhage, etc.), requiring long-term oral anticoagulant drugs (such as aspirin, warfarin) , clopidogrel, etc.); 4) Diagnosis of hemophilia or coagulopathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hematocrit;Hemoglobin; | — |
Countries
China
Contacts
Public ContactXiao Lianbo
Guanghua Hospital, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed