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To investigate whether the stimulation of contralateral motor cortex M1 by inhibitory TUS is helpful to reconstruct bilateral inhibitory balance in stroke patients

Effects and mechanism of low-frequency transcranial ultrasound on upper limb motor function in patients with subcortical cerebral infarction

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900022730
Enrollment
Unknown
Registered
2019-04-23
Start date
2019-06-01
Completion date
Unknown
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral infarction

Interventions

Cases group:Inhibitory ultrasound stimulated motor cortex M1
Health group:Inhibitory ultrasound stimulated motor cortex M1

Sponsors

Ruijin Hospital Affiliated to Shanghai Jiaotong University Medical College
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All subjects volunteered to join and signed the informed consent. Healthy control group: 15 cases. Inclusion criteria: gender, age matched patient group, normal hand grip strength (simple hand grip strength test). Stroke patients: 15 cases. Inclusion criteria: ischemic unilateral basal ganglia stroke, stage I to IV; aged 45-75 years old. Ratio of male to female: 70%/30%. Enrollment time: 1-6 months after stroke.

Exclusion criteria

Exclusion criteria: Healthy control group: 15 cases. Exclusion criteria: patients with intracranial implants, calcification on CT imaging, or symptoms of angiosclerosis. Stroke patients: 15 cases. Exclusion criteria: patients with no motor evoked potential (MEP) on the affected side of the brain, patients with intracranial implantation, patients with calcification points on CT imaging or symptoms of vascular sclerosis, and patients with obvious damage of corpus callosum fiber bundle revealed by DTI imaging examination.

Design outcomes

Primary

MeasureTime frame
Normal side motor evoked potential;Nornal side resting motion threshold;

Countries

China

Contacts

Public ContactWang Pu

Rehabilitation Medicine, Ruijin Hospital Affiliated to Shanghai Jiaotong University Medical College

wangpu_03@126.com+86 18200500874

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026