Crohn's disease
Conditions
Interventions
Gold Standard:Clinical outcome
microbes, 
imaging 
of 
clinical 
subclinical 
CD, 
combined 
with 
and 
Sponsors
The 7th Medical Center of the PLA General Hospital (Army general hospital)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with one of the high-risk conditions of CD were examined by colonoscopy. Once a single or multiple patients with shallow ulcers or erosions were found at the end of the ileum or in different parts of the colon, enrollment and follow-up were determined. High-risk conditions of CD including: patients with unexplained refractory chronic abdominal pain accompanied by changes in bowel habits (including diarrhea, constipation); those with no pain in the right lower quadrant after appendicitis; patients with frequent oral ulcers without cause; unexplained skin, Patients with joint disease; first-degree relatives with IBD; healthy physical examination found in patients with single or multiple aphthous ulcers at the end of the ileum or different parts of the colon.
Exclusion criteria
Exclusion criteria: 1. Diagnosed as advanced CD/ulcerative colitis (UC) or confirmed CD/UC patients are found in screening; 2. Identified patients with other immune diseases, such as Behcet's disease; 3. Combined with pathological considerations for lymph Tumors, suspected tumors and other diseases; 4. People with common intestinal infections (acute and chronic infection, including confirmed intestinal tuberculosis); 5. The intestinal damage caused by oral non-steroidal drugs within 3 months before colonoscopy ; 6. Patients with vascular disease ; 7. Patients with celiac disease; 8. Patients with complication of organ failure; 9. Patients who could not be examined or followed up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum marker;Biomarkers of intestinal flora;Metabolic marker;Pathological feature; | — |
Secondary
| Measure | Time frame |
|---|---|
| Imaging features; | — |
Countries
China
Contacts
Public ContactJianqiu Sheng
The 7th Medical Center of the PLA General Hospital (Army general hospital)
Outcome results
None listed