Psoriasis
Conditions
Interventions
Group H:Intravenous injection of scopolamine 0.03mg/kg + propofol 1ug/ml (TCI mode)
Group L:Intravenous injection of scopolamine 0.01mg/kg + propofol 1ug/ml (TCI mode)
Group C:Tropical treatment
Sponsors
Ruijin Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Volunteer to participate in the trial and sign the informed consent form. 2. Commit to comply with the research process and cooperate with the whole process research; 3. 18 to 65 years old, male or female patients; 4. Patients with chronic psoriasis, the duration of disease = 6 months, the skin lesion area = 10% of BSA or PASI score = 12 when enrolled and received first intervention; 5. ASA score I-III.
Exclusion criteria
Exclusion criteria: 1. Patients with other skin diseases that may affect the assessment of severity; 2. The laboratory test results has shown any of the following abnormalities: WBC 15×10^9/L; neutrophil 35kg/m2) or mental disorder cannot cooperate with the assessment of patients; 14. Other circumstances that the investigator believes are not suitable for the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PASI score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum cytokines;DL-QI scale; | — |
Countries
China
Contacts
Public ContactYu Buwei
Ruijin Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed