Cardiac-Vascular Surgery
Conditions
Interventions
experimental group :acute normolvolemic hemodilution
control group:None
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 65years, no limit on the gender; 2.American Society of Anaesthesiologists (ASA) Score II-III; 3.Body mass index (BMI) of 18 to 31; 4.Elective cardiac valve or large vessel surgery under cardiopulmonary bypass; 5.Written informed consent.
Exclusion criteria
Exclusion criteria: 1.Participating in other clinical trials at the same time; 2.Patients who are unable to cooperate or communicate; 3.Deep Hypothermic Circulatory Arrest; 4.Patients undergoing secondary surgery; 5.Patients with liver, kidney or coagulation insufficiency before operation; 6.History of coronary heart disease or coronary artery reconstructive surgery; 7.According to the formula, the volume of acute blood dilution was estimated to be less than 200ml; 8.Known abusers of alcohol, drugs or narcotics; 9.Women who are pregnant or nursing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative allogeneic blood transfusion rate and transfusion volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemoglobin;Coagulation function;Coagulation function of Preserved autologous blood;Systemic tissue perfusion;Postoperative suction drainage; | — |
Countries
China
Contacts
Public ContactLin Jin
Zhongshan Hospital, Fudan University
Outcome results
None listed