Cognitive Decline
Conditions
Interventions
Combined Intervention Group:Video game combined aerobic exercise training
Video game:Video game training
Aerobic Exercise Group:Aerobic exercise training
Active Control Group:Academic lecture
Sponsors
Institute of Psychology, Chinese Academy of Sciences
Eligibility
Sex/Gender
All
Age
55 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) aged 55-75 years old; (2) community-dwelling; (3) moderate physical activity less than 150 minutes/week in the past 12 months; (4) normal global cognition (scored 24 or more on MoCA); (5) normal activities of daily living; (6) education =9 years; (7) right handed; (8) no history of neurological or psychiatric disorders.
Exclusion criteria
Exclusion criteria: (1) scored 16 or more on CES-D; (2) presence of of diseases that hinder moderate intensity aerobic exercise (including heart disease, heart failure, uncontrolled hypertension, diabetes, severe chronic lung disease, chronic kidney disease, and other diseases that hinder aerobic exercise); (3) stroke or brain injury; (4) require help to walk; (5) schedule conflict with the intervention program.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Memory Test;executive function;Spatial ability;resting-state functional MRI scan;MRI scan;d-MRI scan;Physical activity;Cardiorespiratory fitness;serum BDNF;Working Memory; | — |
Secondary
| Measure | Time frame |
|---|---|
| Language;Mental health; | — |
Countries
China
Contacts
Public ContactJuan Li
Institute of Psychology, Chinese Academy of Sciences
Outcome results
None listed