Prostate Cancer
Conditions
Interventions
Case series:Not Appicable
Sponsors
Fudan University Shanghai Cancer Center
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or older and willing and able to provide informed consent; 2. Histologically or cytologically confirmed adenocarcinoma of the prostate without neuroendocrine differentiation; signet cell; or small cell features; 3. Confirmed castration resistant prostate cancer; 4. Alterations in DNA repair genes are assessed by genetic testing; 5. ECOG = 12 months.
Exclusion criteria
Exclusion criteria: 1. History of another invasive cancer within 3 years of enrollment, with the exception of fully treated cancers with a remote probability of recurrence in the opinion of both the medical monitor and investigator; 2. Any prior medical history that according to the judgement of the investigator might interfere with the subject's granting of informed consent or the safe execution of the procedures required in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Radiologic heterogeneity between lesions detected by nuclear imaging including local/pelvic disease and distant metastatic (M1) disease; | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of radiologic findings with survival;Correlation of radiologic response with treatment schemes; | — |
Countries
China
Contacts
Public ContactDingwei Ye
Fudan University Shanghai Cancer Center
Outcome results
None listed