Colorectal cancer
Conditions
Interventions
Group A:Conventional Laparoscopic Surgery
Group B:NOSES
Sponsors
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The pathological diagnosis was adenocarcinoma; 2. The distance from the tumor to the dentate line is less than 15 cm; 3. Tumors' T stage was T1-T3 before operation; 4. The age of the patients ranged from 18 to 80 years; 5. Body Mass Index (BMI) = 34kg/m2; 6. ECOG score = 3.
Exclusion criteria
Exclusion criteria: 1. ASA Grading > Grade III; 2. Laparoscopic contraindications (such as severe cardiopulmonary insufficiency); 3. Those who had undergone abdominal surgery or had extensive abdominal adhesions in the past; 4. Patients with a history of malignant tumors within 5 years; 5. Patients requiring emergency surgery (such as acute intestinal obstruction); 6. Patients with stage T1 rectal cancer who meet the criteria of transanal local excision; 7. Patients with familial adenomatous polyposis, Lynch syndrome-related rectal cancer and inflammatory bowel disease in active. 8. Patients with Preventive fistula ; 9. Patients with neoadjuvant therapy. 10. Tumors invade adjacent tissues or organs; 11. With distant organ metastasis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Early morbidity rate;Local recurrence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Conversion rate;Peritoneal bacterial contamination;Postoperative recovery and pain score;Functional and quality of life assessments;disease-free survival rate;overall survival rate; | — |
Countries
Turkey
Contacts
Public ContactXishan Wang
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Outcome results
None listed