Coronary heart disease and erectile dysfunction
Conditions
Interventions
Coronary heart disease combined with ED:sildenafil
Coronary heart disease combined with ED:Tadalafil
erectile dysfunction(ED):sildenafil
erectile dysfunction(ED):Tadalafil
Coronary heart disease:None sildenafil or tadalafil
Sponsors
Xiangya Hospital, Central South University
Eligibility
Sex/Gender
Male
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Aged 20 to 65 years, male; (2) NYHA classification is not higher than grade I; (3) Clinical diagnosis of coronary heart disease with ED patients, simple coronary heart disease patients, simple ED patients; (4) Signed informed consent book.
Exclusion criteria
Exclusion criteria: (1) Uncontrollable systemic hemorrhagic disease, bleeding tendency to physical history, anticoagulant and nitrate drugs are currently being used; (2) Blood pressure is not stably controlled; (3) Severe arrhythmia; (4) Unstable angina; (5) Preventing the safe participation of the experimental design and affecting the completion of the study, such as myocardial infarction or stroke, congestive heart failure, severe chronic obstructive pulmonary disease, cancer, diabetes, pregnancy, severe systemic diseases, and Severe psychosis; (6) Allergies to sildenafil or tadalafil; (7) are participating in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IIEF-5;Endothelin-1;Hypersensitive C-reactive protein;Urine nitrite;flow mediated vasodilation;ADMA; | — |
Countries
China
Contacts
Public ContactDongjie Li
Xiangya Hospital, Central South University
Outcome results
None listed