Acute Aortic Sydrome
Conditions
Interventions
Interventional therapy group:Interventional therapy
Operation treatment group:Operation treatment
One-stage interventional therapy for renal artery group:One-stage interventional therapy
Different stages therapy for renal artery group:Different stages therapy
One-stage interventional therapy for coronary artery stenosis group:One-stage interventional therapy
Different stages therapy for coronary artery stenosis group:Different stages therapy
Treatment group of traditional surgery (total arch replacement + elephant nose stent):Traditional surgery (total arch replacement + elephant nose stent)
Debranching technique+Interventional therapy group:Debranching technique+Interventional therapy
Surgery + Branch Artery Intervention Stent Group:Surgery + Branch Artery Intervention Stent
Two covered-stent grafts group:Two covered-stent grafts
Covered-stent graft group:Covered-stent graft
Sponsors
Beijing Anzhen Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Project 2.1: All AAS patients in the multi-center collaboration network were enrolled in this cohort. Informed consent may be waived for patient data collected during hospitalization. Patients who agreed to participate in the follow-up of this cohort were followed up according to the follow-up plan designed in this study; if patients did not agree to follow-up, only the clinical data generated in the hospital were collected. Project 4.1: For PAU, IMH and B type dissection: aged from 18 to 80 years; the symptoms occur within 2 weeks; the intima of dissection is located at the distal end of left subclavian artery; and the anatomical structure is suitable for TEVAR and surgical operation. Project 4.2: For AAS complicated with branch artery stenosis:the age ranged from 18 to 80 years; symptoms occurred within 2 weeks; dissection intima was located at the distal end of left subclavian artery; anatomical structure was suitable for TEVAR; with renal artery stenosis and coronary artery stenosis, more than 50%. Project 4.3: For AAS involving part of arch artery: aged 18-80 years old; symptoms occur within 2 weeks; dissection involving part of arch artery; suitable for patients using chimney technology, windowing technology, branching stent technology or surgical operation. Project 5.1: For AAS involving aortic arch patients: acute AAS patients, aged over 60 years, at least one aortic arch vessel needs revascularization and an informed consent is signed. Project 5.2: For AAS involving the branches of abdominal organs (renal artery):acute type A AASpatients,the intimal rupture is in the renal artery: the rupture is avulsed in the renal artery; the renal artery is thrombosis; consent to sign the informed consent. Project 5.3: For AAS involving thoracoabdominal aorta: typical acute Stanford B type AAS patients; complete clinical and imaging data; anatomical morphology suitakble for endovascular repair; age > 18 years old; signed informed consent.
Exclusion criteria
Exclusion criteria: Project 4.1: For PAU, IMH, B type dissection: AAS secondary to trauma; connective tissue disease (Marfan syndrome or ED syndrome); iatrogenic injury. Project 4.2: For AAS complicated with branch artery stenosis: AAS secondary to trauma; connective tissue disease (Marfan syndrome or ED syndrome); iatrogenic injury. Project 4.3: For AAS involving part of arch artery: AAS secondary to trauma; connective tissue disease (Marfan syndrome or ED syndrome); iatrogenic injury. Project 5.1: For AAS involving aortic arch patients: Patients with connective tissue disease; patients with other vascular lesions (such as coronary artery, carotid artery, lower extremity artery) or heart surgery at the same time during the same operation; patients with clear surgical contraindications. And patients who do not meet the inclusion criteria and are unwilling to participate. Project 5.2: For AAS involving the branches of abdominal organs (renal artery): Renal artery true chamber compression; AAS did not involve the renal artery; acute type B AAS patients; patients with clear surgical contraindications; and patients who did not meet the inclusion criteria and were unwilling to participate. Project 5.3: For AAS involving thoracoabdominal aorta:Secondary treatment after stenting; life expectancy less than 1 year; connective tissue disease patients; pregnant, breast-feeding patients; patients with clear surgical contraindications; and patients who do not meet the inclusion criteria and are unwilling to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serological detection;Imaging data;Primary Endpoint Events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoint events; | — |
Countries
China
Contacts
Public ContactZhang Hongjia
Beijing Anzhen Hospital, Capital Medical University
Outcome results
None listed