The Research based on MRI to investigate the role of tVNS in regulate inflammation and reward loops in Recurrent MDD Patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900022618

Enrollment

Unknown

Registered

2019-04-19

Start date

2019-06-01

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

major depressive disorder

Interventions

taVNS :transcutaneous auricular vagus nerve stimulation

sham taVNS:sham transcutaneous auricular vagus nerve stimulation

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) ICD-10 diagnosis standard of a depressive episode; (2) Aged 18 and 60 years; (3) Hamilton Anxiety ScaleHAMA=7 Meets; (4) Junior high or higher level education; (5) Right-handed; (6) Signing informed consent.

Exclusion criteria

Exclusion criteria: (1) Ongoing addiction to drugs and alcohol; (2) Organic mental disorder; (3) Drug-induced depression; (4) Pregnant women; (5) Postpartum depression.

Design outcomes

Primary

Measure	Time frame
resting-state functional magnetic resonance imaging;Hormone level;Inflammatory marker;	—

Countries

China

Contacts

Public ContactLiu Chunhong

Beijing Hospital of Traditional Chinese Medicine

chunhongliu11@163.com+86 13693384531

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026